Mycophenolate mofetil tablets, 500 mg (often indicated as "IP", referring to the Indian Pharmacopoeia standard) are a prescription immunosuppressant medication used to prevent the body from rejecting a transplanted organ, such as a kidney, heart, or liver. They are typically used in combination with other medicines like corticosteroids and ciclosporin. Key Information
- Primary Use: Prevention of organ rejection in transplant patients. It works by suppressing the immune system so it does not attack the new organ.
- Dosage: The specific dose and frequency are determined by a doctor and depend on the type of transplant and the patient's condition. For kidney transplants, the typical adult dose is 1 gram twice daily (2 g daily dose), while for heart or liver transplants, it is 1.5 grams twice daily (3 g daily dose).
- Administration: Tablets should be swallowed whole; they must not be crushed, chewed, or broken. They are generally taken on an empty stomach, 1 hour before or 2 hours after a meal, unless directed otherwise by a healthcare provider.
- Availability: This medication is available only with a doctor's prescription. Brand names can vary depending on the manufacturer and location (e.g., CellCept, Mycept, Mycofit, Mofilet).
Important Precautions and Warnings
- Pregnancy and Breastfeeding: Mycophenolate mofetil is a powerful human teratogen associated with a high frequency of miscarriage and severe birth defects. It is contraindicated during pregnancy and breastfeeding. Women of childbearing potential must use two forms of effective contraception before, during, and for at least six weeks after treatment.
- Infections and Cancer Risk: The medicine suppresses the immune system, increasing the risk of infections (bacterial, viral, fungal) and certain cancers, particularly skin cancer and lymphoma. Patients should limit sun exposure and use protective clothing and sunscreen.
- Side Effects: Common side effects can include diarrhea, nausea, vomiting, stomach pain, headache, and changes in blood cell counts.
- Monitoring: Regular blood tests are necessary to monitor blood cell counts and kidney and liver function.
- Do Not Stop Abruptly: Do not stop taking this medication without consulting your doctor, as this may lead to rejection of the transplanted organ.
For detailed product information, individuals should refer to the specific Mycophenolate mofetil 500 mg film-coated tablets patient information leaflet provided by the manufacturer or consult a healthcare professional.